Technology Overview

Extracellular Vesicles(EV) Isolation and Purification Technology:

This advanced EV separation and purification technology leverages the benefits of Tangential Flow Filtration (TFF) and Size Exclusion Chromatography (SEC). TFF is first used for preliminary screening to remove most proteins and concentrate the sample. The sample then undergoes further separation of residual proteins in the SEC column. This two-step purification process can handle large sample volumes, facilitating large-scale EV production with minimal protein residue. Additionally, special surface treatment reagents have been developed for the TFF and SEC columns, resulting in higher EV recovery rates and reduced purification time compared to commercial products.

Service for Exosome Analysis and Testing:

Exosomes are vesicles rich in diverse biological molecules, which complicates the elucidation of their mechanisms of action and the implementation of quality control. Our service combines comprehensive exosome characterization with multi-omics analyses to ensure the safety and efficacy of therapeutic exosomes, facilitating faster drug development and improved product quality.

Technical Superiority

Extracellular Vesicles Isolation and Purification Technology:

1. High efficiency – Enables rapid purification from large volumes of cell culture supernatant.

2. High purity – Isolated exosomes/extracellular vesicles retain bioactivity with low protein contamination, outperforming commercial products.

3. Broad sample compatibility – Applicable to various sources, including different cell culture media and plasma.

4. Scalable production – Suitable for large-scale manufacturing and compatible with future automation.

Service for Exosome Analysis and Testing:

1. Multi-omics profiling – Identifies nucleic acids, proteins, and lipids within exosomes.

2. Bioinformatics integration – Supports functional prediction and mechanism analysis.

3. Cross-species compatibility – Applicable to exosome analysis across most species.

Application

Extracellular Vesicles Isolation and Purification Technology:

1. Provides exosome isolation and analysis services for domestic and international partners

2. Enables automated large-scale purification through TFF + SEC integration

Service for Exosome Analysis and Testing:

1. Accelerates drug development by identifying active molecules

2. Enhances product quality and reduces contamination risk

3. Lowers R&D cost through early safety and efficacy assessment

4. Supports process optimization and regulatory compliance