Technology Overview

Immunotherapy activates the patient’s immune system to fight cancer, but immune cell manufacturing is costly due to manual processing, expensive imported systems, and strict environmental requirements.

ITRI’s automated immune cell manufacturing system excels in offering an optimal growth environment for cells with minimized contamination risks. Through precise control and monitoring of temperature, humidity, and gas concentration in a closed cultivation chamber, this solution facilitates the production of stable immune cells in large quantities outside the body.

Technical Superiority

1. Enclosed culture chamber with controlled temperature, humidity, and gas concentration; key modules can be flexibly configured based on the production process

2. Cell activation/transduction module features rotating blades to improve mixing efficiency

3. Bead removal module uses tightly aligned tubing to minimize magnetic bead residue

4. Cell culture bioreactor supports 30 mL and 500 mL culture volumes for 7-day cultivation

5. Automated immune cell culture system enables 7–14 days of continuous cell expansion

Application

1. Immunotherapy

2. CAR-T therapy

3. Cell manufacturing system design and development